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Current evidence supports that antibiotics should be administered 4-6 hours after the patient arrives at the hospital. Because results of definitive diagnostic tests for pneumonia are not available for several days, broad-spectrum antibiotics are prescribed.
The yield of traditional microbiological investigations for diagnosis of CAP is limited for several reasons: routine difficulties in obtaining good-quality sputum and the uncertainty of the value of its culture results, low sensitivity of blood cultures, and administration of antibiotics before samples collection.1
- Sordé, R. et al. (2010) Current and Potential Usefulness of Pneumococcal Urinary Antigen Detection in Hospitalized Patients With Community-Acquired Pneumonia to Guide Antimicrobial Therapy. Arch Intern Med. 27.